Women’s Health & Hormone Therapy
Compounded, prescriber-directed hormone therapy prepared in a USP <800>-compliant workflow at our Florida pharmacy. Every preparation is made to one prescription, for one patient, at the strength and in the dosage form the provider specifies.
Hormones we compound
A reference for prescribers and their patients. Which hormone, which strength, and which form are decisions for the treating provider — Bloom prepares what is prescribed.
Estradiol (E2)
Estradiol is the primary estrogen produced by the ovaries during the reproductive years. Prescribers commonly direct it in perimenopause and menopause protocols to address vasomotor symptoms, sleep disruption, and genitourinary changes, at the lowest dose consistent with the patient's goals and risk profile.
Estriol & Bi-Est
Estriol (E3) is a weaker estrogen, and Bi-Est refers to a compounded combination of estradiol and estriol in a prescriber-specified ratio. Providers who prefer a blended estrogen approach order these when they want to set the ratio and total strength themselves rather than choose from fixed commercial strengths.
Progesterone
Progesterone is the hormone that balances estrogen's effect on the uterine lining. Prescribers routinely add it for patients with a uterus who are receiving estrogen therapy, and often order it as a sustained-release oral capsule taken at night.
Testosterone (low-dose, for women)
Testosterone is present in women at far lower concentrations than in men, and compounded preparations for women are dosed accordingly. Prescribers may include a low-dose topical or troche in a broader hormone protocol; testosterone is a controlled substance, and we prepare it only where our licensure and registrations allow.
DHEA & Pregnenolone
DHEA and pregnenolone are precursor steroids the body converts into other hormones. Some prescribers include them in hormone optimization protocols under their own supervision and monitoring, in oral, topical, or vaginal forms depending on the plan of care.
Dosage forms
The same hormone can be prepared several ways. Prescribers choose the route; we build the preparation around it.
Topical creams & gels
Transdermal bases measured by metered applicator, compounded to the exact strength on the prescription.
Oral capsules
Including sustained-release capsules when the prescriber wants the dose released over a longer window.
Sublingual troches
Flavored lozenges that dissolve under the tongue, often scored so a prescriber can direct a partial dose.
Vaginal creams & suppositories
Local preparations in bases selected for comfort, with applicators sized to the directed dose.
Combination kits
Several coordinated preparations packaged together with clear labeling, so a multi-part regimen arrives in one box.
Why USP <800> matters for hormone therapy
USP <800> — Hazardous Drugs, Handling in Healthcare Settings — sets out how a pharmacy must contain drugs that pose an occupational risk. It sits alongside USP <795> for nonsterile preparations and USP <797> for sterile ones, and it shapes the way we compound hormones every day.
Many hormones are on the NIOSH list
The NIOSH List of Hazardous Drugs includes a number of hormones we compound — estradiol, estriol, progesterone, and testosterone among them. USP <800> applies to how those drugs are received, stored, compounded, packaged, transported, and disposed of.
Containment engineering controls
Hazardous drug compounding takes place in designated, negative-pressure containment areas with containment primary engineering controls and externally vented airflow, so powders and residues stay where they belong.
PPE and closed-system handling
Personnel wear the PPE the standard calls for — chemotherapy-rated gloves, gowns, and eye and respiratory protection as indicated — and use closed-system transfer devices where they are applicable to the preparation.
Deactivation, decontamination, and cleaning
Documented deactivation, decontamination, cleaning, and disinfection procedures run on a defined schedule, backed by written spill-control procedures and hazardous waste segregation.
Training and medical surveillance
Staff who handle hazardous drugs are trained and reassessed against written procedures, and a medical surveillance program is part of the same framework. The point of all of it is straightforward: protect our staff, protect the patient receiving the preparation, and protect the environment.
How we work with prescribers
Bloom does not diagnose, treat, or prescribe. We prepare and dispense what a licensed provider orders, and we make that easy to adjust as care evolves.
Patient-specific dosing
You set the hormone, the strength, the base, and the route. We compound to that order for that patient — nothing is made ahead to a standard strength.
Strength adjustments between refills
When a follow-up visit calls for a different strength or ratio, send the new prescription and we prepare the next fill to it. No fixed commercial increments to work around.
Titration support
We can prepare a series of strengths or scored forms that make a stepwise titration practical, and we keep the labeling clear so patients follow your directions accurately.
Pharmacist consultation
Our pharmacists are available to talk through bases, dosage forms, stability, and beyond-use dating before you write, and to answer patient questions about how a preparation is used and stored.
Discreet direct-to-patient shipping
Preparations ship in plain, tamper-evident packaging directly to the patient, within the states where we are licensed (currently Florida), or to your practice when you prefer to dispense in office.
Important safety information
Compounded hormone preparations are not FDA-approved. They have not been evaluated by the FDA for safety, effectiveness, or quality. They are prepared and dispensed only pursuant to a prescription written by a licensed provider for an individual patient, based on that patient’s needs.
Estrogen products carry boxed warnings, including endometrial cancer, cardiovascular disorders, breast cancer, and probable dementia. Estrogens should not be used to prevent cardiovascular disease or dementia. Patients should review the full warnings, contraindications, and side effects with their prescriber before starting therapy and at every follow-up.
Bloom Pharmacy does not diagnose, treat, or prescribe. Nothing on this page is medical advice, and nothing here is a claim about what any preparation will do for a given patient. Talk to your provider about whether hormone therapy is appropriate for you.
About this page
The descriptions above are general background on hormones and dosage forms a prescriber may order. They are not a recommendation, a treatment plan, or a statement that any therapy is safe or effective for you. Dosing, monitoring, and the decision to start or stop therapy belong to your provider.